WHO Classification of Bone Tumours

نویسندگان

  • H. D. Dorfman
  • D. Vanel
  • B. Czerniak
  • Y. K. Park
  • R. Kotz
  • K. K. Unni
چکیده

Primary neoplasms of the skeleton are rare, amounting to only 0.2% of the overall human tumour burden. However, children are frequently affected and the aetiology is largely unknown. Significant progress has been made in the histological and genetic typing of bone tumours. Furthermore, advances in combined surgical and chemotherapy havelead to a significant increase in survival rates even for highly malignant neoplasms, including osteosarcoma and Ewing sarcoma. Several bone tumours occur in the setting of inherited tumour syndromes, but their histology differs little from the respective sporadic counterparts.

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تاریخ انتشار 2006